Protein Details: Gap junction delta-3 protein

Protein ID

ICDB_Pro_1280

Protein Name

Gap junction delta-3 protein

Gene Name

GJD3; GJA11; GJC1

Organism

Homo sapiens (Human)

Length

294 amino acids

AlphaFoldDB

AF-Q8N144-F1-model_v4.pdb

Function

Sequence

MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGERDNRCNRAHEEAQKLLPPPPPPPPPPALPSRRPGPEPCAPPAYAHPAPASLRECGSGRGKASPATGRRDLAI

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Ohdo Syndrome;Sbbys Variant and Ohdo Syndrome

Location

Expressed in vascular smooth muscle cells. Found in heart; colon; and artery (at protein level). Found in cerebral cortex; heart; liver; lung; kidney; spleen and testis. Found in cerebral cortex; heart; liver; lung; kidney; spleen and testis. Found in cerebral cortex; heart; liver; lung; kidney; spleen and testis.

DOI ID

10.1074/jbc.m205348200; 10.1152/ajpcell.00163.2002; 10.1038/ng1285

RefSeq

NP_689343.3 [Q8N144-1]